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Quite a few receptor-mediated activities display the phenomenon of desensitization, meaning that continued or repeated administration of the drug makes a progressively lesser effect. Among the many complicated mechanisms associated are conversion of your receptors to some refractory (unresponsive) condition from the existence of the agonist, to ens

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Over a winter afternoon in Quincy, Mass., I satisfied with Stephen Duclos, a relatives, couples and intercourse therapist, in his Office environment, before his evening individuals arrived. Artwork hung around the walls, the windows stretched almost from the ground to your ceiling and punctiliously organized publications lined his shelves. Duclos,

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